https://checkout.basepaws.com/blogs/news/tagged/category_feline-genetics

Acute Intermittent Porphyria in Cats: Background, Breeds at Risk, Symptoms, Diagnosis, and Treatment

Acute Intermittent Porphyria in Cats: Background, Breeds at Risk, Symptoms, Diagnosis, and Treatment

Porphyrias is a term for a group of rare metabolic disorders that affect a cat’s ability to produce heme. Heme is an essential part of hemoglobin—a protein found in red blood cells that brings oxygen from a cat’s lungs to other parts of their body. Different types of porphyrias can occur in cats, as well as in humans and other animals. In this blog, we’ll discuss acute intermittent porphyria (AIP) in cats, its symptoms, and how it is diagnosed and treated by veterinarians.

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Pyruvate Kinase Deficiency: Background, Breeds at Risk, Symptoms, and Treatment

Pyruvate Kinase Deficiency: Background, Breeds at Risk, Symptoms, and Treatment

Pyruvate kinase is an enzyme involved in the metabolism of red blood cells. When mutations in the PKLR gene occur, it reduces the functionality of  this enzyme and subsequently affects the ability of red blood cells to survive and function properly. Learn about pyruvate kinase deficiency in cats, symptoms and treatment, and the cat breeds that are known to be at a higher risk for this condition.

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Epistasis in Cat Coat Genetics

Epistasis in Cat Coat Genetics

Today, we’re decoding one of the mysteries of genetics that relates to your Basepaws DNA report of results. It's called epistasis. When epistasis occurs, the observable expression (phenotype) of a genesuch as one responsible for the color of your kitty's coatgets modified in some way by a completely different gene that has the ability to mask, suppress, or inhibit how that coat color gene is expressed. Epistasis helps explain why sometimes you may get a “likely to have” result for a genetic trait in your cat’s Basepaws report that doesn’t quite match up with their physical appearance.
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Genetic Health + Trait Marker Changes to the Basepaws Report

Genetic Health + Trait Marker Changes to the Basepaws Report

From time to time, we update the Basepaws digital report of results for our Breed + Health Cat DNA Test. Today, we’d like to take a moment to share some details about two recent changes to our report—one for a genetic health marker linked to the common cat heart condition hypertrophic cardiomyopathy, and one for a genetic trait marker associated with the Siamese colorpoint coat pattern
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Basepaws Feline Cancer Research

Basepaws Feline Cancer Research

Too many pet parents have known the heartbreaking loss of a beloved pet to cancer. As part of our commitment to helping all pets live healthier, happier, and longer lives, Basepaws is studying the genetic and oral microbiome factors associated with certain types of cancer. We welcome your participation in this research, which could inform the development of new screening tests for earlier detection of cancer in pets.
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